Author : Derek Le Roith

Published in : Humana press

ISBN No.  : 978-1-59745-572-5

File Type : pdf

File Size : 6 mb

Language : English


Undoubtedly, there is a worldwide epidemic of obesity, the metabolic syndrome and type 2 diabetes, and with these changes comes controversy! What is the cause of the obesity epidemic? Is the increase in type 2 diabetes caused by obesity alone or are there other factors involved, such as genetics? Is the metabolic syndrome truly a syndrome or merely a grouping of risk factors for cardiovascular disease? How do we effectively prevent and treat the epidemics of obesity, diabetes, and their devastating complications? This book is a compilation of discussions by world experts on these topics. Each chapter was chosen to cover many of the issues that investigators, academics, and healthcare professionals have to deal with in their institutions and private practice. Stress and dietary excess are presented by Rena Wing, and the explosion of childhood obesity is discussed by Desmond Schatz. On the other hand, treatments for obesity, metabolic syndrome, and hyperlipidemia are discussed separately by Drs Kaplan, Meigs, and Goldberg, respectively; very practical approaches are presented. The treatment of type 2 diabetes and the anticipation that this would prevent complications are discussed by Vivian Fonseca. Julio Rosenstock presents the case for earlier introduction of insulin in the armamentarium for treating type 2 diabetics. Werner Walthausal presents the pros and cons for a polypill that potentially should improve patient compliance. Incretins are the "new kid on the block" with regard to therapeutic agents and are discussed by Jens Holst. The exciting new concept for hospitalized diabetics (and hyperglycemic nondiabetics) is the use of intensive insulin therapy to manage the hyperglycemia more effectively and reduce mortality and morbidity. This is discussed by Greet van den Berghe, who pioneered the studies.
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