ACS CHEMICAL BIOLOGY: VOLUME 5, ISSUE 11

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FILE TYPE : zip ( in under pdf )


JOURNAL TITLE : ACS Chemical Biology


LANGUAGE : ENGLISH


ISSUE DATE : 19 NOV 2010


pages : 995 - 1086

DESCRIPTION

The structure of Binucleine 2, a small molecule inhibitor of Drosophila Aurora B kinase is shown interacting with an isoleucine residue. The foreground also has the drawing of a common fruit fly (Drosophila melanogaster). The background image shows a sequence alignment of Aurora kinases from different organisms and the “I” circled in red depicts the unique isoleucine residue present in the Drosophila Aurora B kinase. 
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