Na+-H+ Exchange, lntracellular pH, and Cell Function Volume 26 (PDF)

Na+-H+ Exchange, lntracellular pH, and Cell Function Volume 26

Author: Arnost Kleinzeller and Felix Bronner
Release at: 1986
Pages: 331
Volume: 26 Volume
File Size: 14 MB
File Type: PDF
Language: English



Description of Na+-H+ Exchange, lntracellular pH, and Cell Function Volume 26 (PDF)

Na+-H+ Exchange, lntracellular pH, and Cell Function by Arnost Kleinzeller & Felix Bronner is a great book available for (eBook) PDF download. Since 1975, the Yale University Department of Physiology has sponsored annual symposia on topics concerned with membrane transport processes. The goal of the symposium held on December 13-15, 1984 was to describe the properties of the plasma membrane Nat -H + exchanger, to discuss its role and that of other acid-base transport systems in the regulation of intra cellular pH, and to relate Na+-H+ exchange and intra cellular pH to other important aspects of cell function. For this purpose, a group of distinguished scientists from diverse disciplines was assembled, and they have contributed the chapters to this volume.

We gratefully acknowledge the invaluable assistance of Linda Brouard, our conference coordinator, whose efforts contributed so greatly to the success of the symposium. We wish also to acknowledge the generous financial support of the Kroc Foundation, the Burroughs Wellcome Co., Stuart Pharmaceuticals, McNeil Pharmaceutical, Hoechst Pharmaceuticals, Inc., Americas, Inc., Miles Laboratories, Merck Sharp and Dohme, and WPI, Inc.




Content of Na+-H+ Exchange, lntracellular pH, and Cell Function Volume 26 (PDF)


PART I GENERAL ASPECTS OF INTRACELLULAR pH REGULATION AND Na+-H+ EXCHANGE

Chapter 1: lntracellular pH Regulation by Leech and Other Invertebrate Neurons

Chapter 2: Approaches for Studying lntracellular pH Regulation in Mammalian Renal Cells

Chapter 3: Aspects of pHi Regulation in Frog Skeletal Muscle

Chapter 4: Molecular Properties and Physiological Roles of the Renal Na+- H + Exchanger

PART II Na+-H+ EXCHANGE AND CELL VOLUME REGULATION

Chapter 5: Volume-Sensitive Alkali Metal-H Transport in Amphiuma Red Blood Cells

Chapter 6: Na-Proton Exchange in Dog Red Blood Cells

Chapter 7: Activation of the Na+-H+ Antiport by Changes in Cell Volume and by Phorbol Esters; Possible Role of Protein Kinase

PART III Na+-H+ EXCHANGE AND CONTROL OF CELL GROWTH

Chapter 8: The Generation of Ionic Signals by Growth Factors

Chapter 9: Control of Mitogenic Activation of Na+-H+ Exchange

Chapter 10: Mechanisms of Growth Factor Stimulation of Na+-H+ Exchange in Cultured Fibroblasts

Chapter 11: B Lymphocyte Differentiation: Role of Phosphoinositides, C Kinase, and Na+-H+ Exchange

Chapter 12: Na+-H+ Exchange and Growth Control in Fibroblasts: A Genetic Approach

PART III ROLE OF Na+-H+ EXCHANGE IN HORMONAL AND ADAPTIVE RESPONSES

Chapter 13: Hormonal Regulation of Renal Na+-H+ Exchange Activity

Chapter 14: Adaptation of Na+-H+ Exchange in the Proximal Tubule: Studies in Microvillus Membrane Vesicles

Chapter 15: The Role of lntracellular pH in Insulin Action and in Diabetes Mellitus

Chapter 16: The Proton as an Integrating Effector in Metabolic Activation

Index

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