| Author: | Arnost Kleinzeller and Felix Bronner |
| Release at: | 1986 |
| Pages: | 331 |
| Volume: | 26 Volume |
| File Size: | 14 MB |
| File Type: | |
| Language: | English |
Description of Na+-H+ Exchange, lntracellular pH, and Cell Function Volume 26 (PDF)
Na+-H+ Exchange, lntracellular pH, and Cell Function by Arnost Kleinzeller & Felix Bronner is a great book available for (eBook) PDF download. Since 1975, the Yale University Department of Physiology has sponsored annual symposia on topics concerned with membrane transport processes. The goal of the symposium held on December 13-15, 1984 was to describe the properties of the plasma membrane Nat -H + exchanger, to discuss its role and that of other acid-base transport systems in the regulation of intra cellular pH, and to relate Na+-H+ exchange and intra cellular pH to other important aspects of cell function. For this purpose, a group of distinguished scientists from diverse disciplines was assembled, and they have contributed the chapters to this volume.
We gratefully acknowledge the invaluable assistance of Linda Brouard, our conference coordinator, whose efforts contributed so greatly to the success of the symposium. We wish also to acknowledge the generous financial support of the Kroc Foundation, the Burroughs Wellcome Co., Stuart Pharmaceuticals, McNeil Pharmaceutical, Hoechst Pharmaceuticals, Inc., Americas, Inc., Miles Laboratories, Merck Sharp and Dohme, and WPI, Inc.
Content of Na+-H+ Exchange, lntracellular pH, and Cell Function Volume 26 (PDF)
PART I GENERAL ASPECTS OF INTRACELLULAR pH REGULATION AND Na+-H+ EXCHANGE
Chapter 1: lntracellular pH Regulation by Leech and Other Invertebrate Neurons
Chapter 2: Approaches for Studying lntracellular pH Regulation in Mammalian Renal Cells
Chapter 3: Aspects of pHi Regulation in Frog Skeletal Muscle
Chapter 4: Molecular Properties and Physiological Roles of the Renal Na+- H + Exchanger
PART II Na+-H+ EXCHANGE AND CELL VOLUME REGULATION
Chapter 5: Volume-Sensitive Alkali Metal-H Transport in Amphiuma Red Blood Cells
Chapter 6: Na-Proton Exchange in Dog Red Blood Cells
Chapter 7: Activation of the Na+-H+ Antiport by Changes in Cell Volume and by Phorbol Esters; Possible Role of Protein Kinase
PART III Na+-H+ EXCHANGE AND CONTROL OF CELL GROWTH
Chapter 8: The Generation of Ionic Signals by Growth Factors
Chapter 9: Control of Mitogenic Activation of Na+-H+ Exchange
Chapter 10: Mechanisms of Growth Factor Stimulation of Na+-H+ Exchange in Cultured Fibroblasts
Chapter 11: B Lymphocyte Differentiation: Role of Phosphoinositides, C Kinase, and Na+-H+ Exchange
Chapter 12: Na+-H+ Exchange and Growth Control in Fibroblasts: A Genetic Approach
PART III ROLE OF Na+-H+ EXCHANGE IN HORMONAL AND ADAPTIVE RESPONSES
Chapter 13: Hormonal Regulation of Renal Na+-H+ Exchange Activity
Chapter 14: Adaptation of Na+-H+ Exchange in the Proximal Tubule: Studies in Microvillus Membrane Vesicles
Chapter 15: The Role of lntracellular pH in Insulin Action and in Diabetes Mellitus
Chapter 16: The Proton as an Integrating Effector in Metabolic Activation
Index
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