Bacterial Metabolism

Bacterial Metabolism
Gerhard Gottschalk
Publisher: Springer-Verlag Berlin Heidelberg
ISBN No: 978-1-4612-1072-6
Release at: 1986
Pages: 370
Second Edition
File Size: 28 MB
File Type: pdf
Language: English

Description of Bacterial Metabolism

Progress in certain areas of bacterial metabolism has been rapid since the first edition of this book was published. Consequently, large parts of it had to be rewritten or extensively revised for a second edition. Some new material has also been included, sections on chemotaxis, bioluminescence, and catabolic plasmids. 

The use of NAD, NADP, NADH2, and NADPH2 as abbreviations throughout the first edition of the book has been criticized by some reviewers. The author has taken this to heart; the abbreviations for these coenzymes have been changed to NAD+, NADH + H+, etc.

Content of Bacterial Metabolism


Nutrition of Bacteria
I. Major and Minor Bioelements
II. The Two Basic Mechanisms of ATP Synthesis
III. Nutrients as Energy Sources
IV. Growth Factor Requirements of Bacteria
V. Summary


How Escherichia coli Synthesizes ATP during Aerobic Growth on Glucose
I. Transport of D-Glucose into the E. coli Cell 13
II. Degradation of Glucose-6-Phosphate to Pyruvate via the Embden-Meyerhof-Parnas (EMP) Pathway 15
III. Oxidative Decarboxylation of Pyruvate to Acetyl-Coenzyme A 18
IV. Oxidation of Acetyl-CoA via the Tricarboxylic Acid Cycle 20
V. The Formation of ATP in the Respiratory Chain 22
VI. Summary 35


Biosynthesis of Escherichia coli Cells from Glucose
I. Composition of E. coli Cells
II. Assimilation of Ammonia
Ill. Assimilatory Reduction of Sulfate
IV. Biosynthesis of Amino Acids
V. How Pentose Phosphates and NADPH are Formed
VI. Ribonucleotides and Deoxyribonucleotides
VII. Biosynthesis of Lipids
VIII. Formation of Carbohydrates
IX. Synthesis of Polymers
X. The Requirement for an Anaplerotic Sequence
XI. Summary


Aerobic Growth of Escherichia coli on Substrates Other Than Glucose
I. Fructose and Lactose as Substrates
II. Pentoses as Substrates
Ill. Acetate, Pyruvate, and L-Malate as Substrates
IV. Summary


Metabolic Diversity of Aerobic Heterotrophs
I. The Different Mechanisms for the Uptake of Substrates
II. The Entner-Doudoroff Pathway
III. Sugar Degradation via the Pentose Phosphate Cycle
IV. The Methylglyoxal Bypass
V. Diversity in Energy Metabolism
VI. Dissimilatory Reduction of Nitrate
VII. Bacterial Bioluminescence
VIII. Alternate Anaplerotic Sequences
IX. Biosynthesis of Monomers and Polymers
X. Summary


Catabolic Activities of Aerobic Heterotrophs
I. Degradation of Polymers by Exoenzymes
II. Growth with Amino Acids
Ill. Growth with Organic Acids
IV. Growth with Aliphatic Hydrocarbons
V. Growth with Aromatic Compounds
VI. Growth with C, Compounds
VII. Incomplete Oxidations
VIII. Plasmid-Encoded Catabolic Activities
IX. Summary


Regulation of Bacterial Metabolism
I. Regulation of Enzyme Synthesis by Induction and Repression
II. Regulation of Enzyme Activity
Ill. Summary


Bacterial Fermentations
I. Alcohol Fermentation
II. Lactate Fermentation
Ill. Butyrate and Butanol-Acetone Fermentation
IV. Mixed Acici and Butanediol Fermentation
V. Propionate and Succinate Fermentation
VI. Acetate Fermentation
VII. Methane Fermentation
VIII. Sulfide Fermentation (Desulfurication)
IX. The Anaerobic Food Chain
X. Fermentation of Nitrogenous Compounds
XI. Summary


Chemolithotrophic and Phototrophic Metabolism
I. Chemolithotrophic Metabolism
II. Assimilation of CO,
Ill. Phototrophic Metabolism
IV. Summary


Fixation of Molecular Nitrogen
I. Nitrogen-fixing Organisms
II. Biochemistry of Nitrogen Fixation
III. Regulation of Nitrogenase
IV. Summary
Further Reading
Index of Organisms
Subject Index

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