Biology of Chlamydia

Georg Häcker
Publisher: Springer International Publishing
ISBN No: 978-3-319-71232-1
Release at: 2018
Pages: 243
First Edition
File Size: 4 MB
File Type: pdf
Language: English

Description of Biology of Chlamydia

Chlamydiae are obligate intracellular bacteria. They live in an intracellular vacuole (the inclusion) that they customize to permit the delivery of nutrients and to provide protection against host cell defenses. Chlamydiae have two developmental forms: one is infectious (the elementary body) but has little metabolism and the other one divides very actively but is not infectious (the reticulate body). 
Once a cell is infected, EBs differentiate to RBs; after a cycle of about two days, re-differentiated EBs are released, either by lysis of the host cell or by the active release of intact inclusions. 

Content of Biology of Chlamydia

Deconstructing the Chlamydial Cell Wall 1
Anna Klöckner, Henrike Bühl, Patrick Viollier, and Beate Henrichfreise
One Face of Chlamydia trachomatis: The Infectious
Elementary Body  35
Mathilde M. Cossé, Richard D. Hayward and Agathe Subtil
Manipulation of the Host Cell Cytoskeleton by Chlamydia  59
Ana T. Nogueira, Antonio T. Pedrosa, and Rey A. Carabeo
Subversion of Cell-Autonomous Host Defense by
Chlamydia Infection  81
Annette Fischer and Thomas Rudel
The Hidden Genomics of Chlamydia trachomatis  107
James Hadfield, Angèle Bénard, Daryl Domman, and Nicholas Thomson
Advances and Obstacles in the Genetic Dissection of Chlamydial
Virulence  133
Julie A. Brothwell, Matthew K. Muramatsu, Guangming Zhong
and David E. Nelson
Chlamydia trachomatis as the Cause of Infectious Infertility:
Acute, Repetitive or Persistent Long-Term Infection?  159
Larissa Schuchardt and Jan Rupp
Immunopathogenesis of Chlamydial Infections 183
Ashley K. Murthy, Weidong Li, and Kyle H. Ramsey
Chlamydia trachomatis: Protective Adaptive Responses and Prospects
for a Vaccine. 217

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