Author: |
Jeremy W. Dale, Simon F. Park
|
Release at: | 2010 |
Pages: | 403 |
Edition: |
5th Edition
|
File Size: | 8 MB |
File Type: | |
Language: | English |
Description of Molecular Genetics of Bacteria 5th Edition (PDF)
Molecular Genetics of Bacteria 5th edition by Jeremy W. Dale, Simon F. Park is a great bacterial Genetics book available in (PDF) download. In the preface to the fourth edition (published in 2004) we referred to the revolution in bacterial genetics that was started by gene cloning and sequencing, coupled with related techniques such as the polymerase chain reaction (PCR) and microarrays, and culminated in the knowledge of genome sequences of a rapidly expanding range of bacteria. This posed a dilemma. How could we accommodate these new techniques, and the wealth of exciting new information they provided, while not losing sight of classical bacterial genetics? This dilemma has become even more acute.
True, many of the older methods are now no longer used and could be relegated to the pages of history. But there is a danger of throwing out the baby with the bathwater. Not only is there a need to maintain some sense of how the subject has got to the stage we are now at, but also a discussion of some of these methods is useful in establishing an understanding of how bacterial genetics operates in natural environments. Genetics is not just about how we find out about bacteria: it is about how bacteria have evolved, and continue to evolve and continue to adapt to changing environments. Molecular genetics, in isolation, is essentially reductionist. Even genome sequencing, and global analysis of gene expression, by themselves merely provide catalogs of genes. Ultimately, those lists have to be related to the behavior of the whole organism, and from there to how organisms interact with one another and with their environment.
Content of Molecular Genetics of Bacteria 5th Edition (PDF)
Chapter 1: Nucleic Acid Structure and Function
Chapter 2: Mutation and Variation
Chapter 3: Regulation of Gene Expression
Chapter 4: Genetics of Bacteriophages
Chapter 5: Plasmids
Chapter 6: Gene Transfer
Chapter 7: Genomic Plasticity: Movable Genes and Phase Variation
Chapter 8: Genetic Modification: Exploiting the Potential of Bacteria
Chapter 9: Genetic Methods for Investigating Bacteria
Chapter 10: Gene Mapping to Genomics and Beyond
Appendix A Further Reading
Appendix B Abbreviations Used
Appendix C Glossary
Appendix D Enzymes and other Proteins
Appendix E Genes
Appendix F Standard Genetic Code
Appendix G Bacterial Species
Index
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