Antisepsis, Disinfection, and Sterilization 2nd edition (PDF)

Antisepsis, Disinfection, and Sterilization 2nd edition

Author:
Gerald E. McDonnell
Release at: 2017
Pages: 433
Edition:
2nd Edition (Types, Action, and Resistance)
File Size: 18 MB
File Type: pdf
Language: English



Description of Antisepsis, Disinfection, and Sterilization 2nd Edition (PDF)

Antisepsis, Disinfection, and Sterilization 2nd Edition by Gerald E. McDonnell is a great book for study Medical Science available in PDF download. The control of microorganisms and microbial growth is an important consideration in medical, veterinary, dental, industrial, pharmaceutical, environmental, and food processing settings. This book has been developed to provide a basic understanding of the various chemical and physical antisepsis, disinfection, and sterilization methods used for infection prevention and contamination control. Disinfection and sterilization technologies are used for the control of microorganisms on surfaces, in products, or in air, while antisepsis is particularly associated with microbial reduction on the skin or mucous membranes. Many of these applications have been used over many years and continue to play important roles in our daily lives, including the provision of safe drinking water, production and preservation of products, laboratory safety, food safety, sterilization of medical devices, and disinfection of critical surfaces. The benefits of microbial control have been appreciated since ancient times—for example, in the use of heating, salts, and metals for preservation and wound treatment—despite the absence in those times of any pure understanding of microbiology.

Over the last 160 years, we have gained a greater appreciation of microorganisms and their roles in contamination and infection. In parallel, various chemical and physical antisepsis, disinfection, and sterilization methods have been developed and are widely used to render surfaces and products safe for use. Despite these advancements, microbial control issues continue to challenge us. Notable examples include controlling the risk of virus transmission in outbreaks of Zika virus, Ebola virus, and noroviruses; medical device contamination associated with health care outbreaks of infection (such as with flexible endoscopes); the emerging concerns with unique infectious agents (such as prions or other transmissible proteinaceous agents); and the continuing concern of anti-infective (including antibiotic)-resistant microorganisms in hospitals and the general community. As our knowledge increases in microbiology, so does our understanding of the novel ways that microorganisms can present with mechanisms of surviving the many broad-spectrum contamination control technology that we use, including chemical and physical disinfection and sterilization methods.




Content of Antisepsis, Disinfection, and Sterilization 2nd Edition (PDF)


Chapter 2: Introduction

  • General introduction
  • Definitions
  • General microbiology
  • Introduction
  • Eukaryotes & prokaryotes
  • Eukaryotes
  • Multicellular eukaryotes
  • Fungi
  • Algae
  • Protozoa
  • Prokaryotes
  • Eubacteria
  • Archaea
  • Viruses
  • Prions
  • Toxins
  • General considerations
  • Microbial resistance
  • Evaluation of efficacy
  • Suspension testing
  • Surface testing
  • In-use testing
  • Biological, chemical, and other indicators
  • Parametric control
  • Microscopy and other techniques
  • Disinfection versus sterilization
  • Choosing a process or product
  • Guidelines and standards
  • Formulation effects
  • Process effects
  • The importance of surface cleaning
  • Water quality
  • Chapter 2: Physical Disinfection

  • Introduction
  • Heat
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Cold temperatures
  • Radiation
  • Isotopes
  • Electromagnetic radiation
  • Types
  • Ultraviolet
  • Infrared
  • Microwaves
  • Applications
  • UV
  • Infrared
  • Microwaves
  • Spectrum of activity
  • UV
  • Infrared
  • Microwaves
  • Advantages
  • UV
  • Infrared
  • Microwaves
  • Disadvantages
  • UV
  • Infrared
  • Microwaves
  • Mode of action
  • UV
  • Infrared
  • Microwaves
  • Filtration
  • Types and applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Chapter 3: Chemical Disinfection

  • Introduction
  • Acids and acid derivatives
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Alkalis or bases
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Aldehydes
  • Types
  • Applications
  • Glutaraldehyde and OPA
  • Formaldehyde
  • Spectrum of activity
  • Glutaraldehyde
  • Formaldehyde
  • Advantages
  • Glutaraldehyde and OPA
  • Formaldehyde
  • Disadvantages
  • Glutaraldehyde and OPA
  • 2 Formaldehyde
  • Mode of action
  • Glutaraldehyde and OPA
  • Formaldehyde
  • Alcohols
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Anilides
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Antimicrobial dyes
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Biguanides
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Diamidines
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Essential oils and plant extracts
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Halogens and halogen-releasing agents
  • Types
  • Applications
  • Iodine
  • Chlorine
  • Bromine
  • Spectrum of activity
  • Iodine
  • Chlorine
  • Bromine
  • Advantages
  • Iodine
  • Chlorine
  • Bromine
  • Disadvantages
  • Iodine
  • Chlorine
  • Bromine
  • Mode of action
  • Iodine
  • Chlorine
  • Bromine
  • Metals
  • Types
  • Applications
  • Copper
  • li>Silver
  • Spectrum of activity
  • Copper
  • Silver
  • Advantages
  • Copper
  • Silver
  • Disadvantages
  • Copper
  • Silver
  • Mode of action
  • Copper
  • Silver
  • Peroxygens and other forms of oxygen
  • Types
  • Applications
  • Ozone
  • Hydrogen peroxide
  • PAA
  • Chlorine dioxide
  • Spectrum of activity
  • Ozone
  • Hydrogen peroxide
  • PAA
  • Chlorine dioxide
  • Advantages
  • Ozone
  • Hydrogen peroxide
  • PAA
  • Chlorine dioxide
  • Disadvantages
  • Ozone
  • Hydrogen peroxide
  • PAA
  • Chlorine dioxide
  • Mode of action
  • Ozone
  • Hydrogenperoxide
  • PAA
  • Chlorine dioxide
  • Phenolics
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Antiseptic phenolics
  • Types
  • Applications
  • Antimicrobial activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Triclosan
  • Chloroxylenol
  • Salicylic acid
  • Quaternary ammonium compounds and surfactants
  • Types
  • Applications
  • Antimicrobial efficacy
  • Advantages
  • Disadvantages
  • Mode of action
  • Other miscellaneous biocides or applications
  • Pyrithiones
  • Isothiazolones derivatives
  • Biocides integrated into surfaces
  • Micro- or nano-particles
  • Antimicrobial enzymes, proteins, or peptides
  • Bacteriophages
  • Chapter 4: Antiseptics and Antisepsis

  • Introduction
  • Some definitions specific to antisepsis
  • Structure of skin
  • Skin microbiology
  • Antiseptic applications
  • Routine skin washing/antisepsis
  • Pretreatment of skin prior to surgic
  • intervention
  • Treatment of skin or wound
  • infections
  • Treatment of oral and other mucous membranes
  • Material-integrated applications
  • Biocides used as antiseptics
  • General considerations
  • Major types of biocides in antiseptics
  • Other antiseptic biocides
  • Chapter 5: Physical Sterilization

  • Introduction
  • Moist heat sterilization
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Dry heat sterilization
  • Types
  • Applications
  • Advantages
  • Disadvantages
  • Mode of action
  • Radiation sterilization
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Filtration
  • Other physical sterilization methods
  • Plasma
  • Pulsed light
  • Supercritical fluids
  • Pulsed electric fields
  • Chapter 6: Chemical Sterilization

  • Introduction
  • Epoxides
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Low temperature steam-formaldehyde
  • Types and applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • High temperature formaldehyde-alcohol Types and applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Hydrogen peroxide
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • her oxidizing agent-based processes
  • Liquid peracetic acid
  • Electrolyzed water
  • Types
  • Applications
  • Spectrum of activity
  • Advantages
  • Disadvantages
  • Mode of action
  • Gaseous peracetic acid
  • Ozone
  • Chlorine dioxide
  • Nitrogen dioxide
  • Chapter 7: Mechanisms of Action

  • Introduction
  • Anti-infectives
  • Antibacterials (antibiotics)
  • Antifungals
  • Antivirals
  • Antiparasitic drugs
  • Macromolecular structure
  • General mechanisms of action
  • Introduction
  • Oxidizing agents
  • Cross-linking or coagulatingagents
  • Transfer of energy
  • Other structure-disrupting agents
  • Chapter 8: Mechanisms of Microbial Resistance

  • Introduction
  • Biocide/microorganism interaction
  • Intrinsic bacterial resistance mechanisms
  • General stationary phase phenomenon
  • Motility and chemotaxis
  • Stress responses
  • Efflux mechanisms
  • Enzymatic and chemical protection
  • Intrinsic mechanisms to heavy metals
  • Capsules, slime formation, and S-layers
  • Biofilm development
  • Bacteria with extreme intrinsic resistance
  • Extremophiles
  • Dormancy
  • Revival mechanisms
  • Intrinsic resistance of mycobacteria
  • Intrinsic resistance of other Gram-positive bacteria
  • Intrinsic resistance of Gram-negative bacteria
  • Acquired bacterial resistance mechanisms
  • Introduction
  • Mutational resistance
  • Plasmids and transmissible elements
  • Mechanisms of viral resistance
  • Mechanisms of prion resistance
  • Mechanisms of fungal resistance
  • Mechanisms of resistance in other eukaryotic microorganisms
  • Index

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