| Author: |
T.A. Brown
|
| Release at: | 2018 |
| Pages: | 539 |
| Edition: |
4th Edition
|
| File Size: | 78 MB |
| File Type: | |
| Language: | English |
Description of Genomes 4th Edition
Genomes 4th edition written by T.A. Brown is a great book for Genetics related studies available in ebook (PDF) to get a printable download. There have been remarkable advances in our knowledge of genomes since the previous edition of this book was published ten years ago. Back in 2007, next-generation sequencing was in its infancy and high-throughput meth-ods for transcriptomics and proteomics were only beginning to be exploited. The application of these methods over the last ten years has resulted in an exponential increase in the number of species for which genome sequences and annotations are now available and single species to be examined by multiple versions of the genome.
The profusion of new sequences has had a particularly dramatic impact on bacterial genomics, with the introduction of the pan-genome concept and the discovery of extensive lateral transfer of genes between species. Our knowledge of eukaryotic genomes has an under-gone equally dramatic change, with the discovery of new types of noncoding RNA, including the vast numbers of long RNAs that are transcribed from the supposedly intergenic regions of many genomes.
Genomes 4th edition retains the overall structure of the previous editions, with the book divided into four parts, on genome sequencing and annotation, genome anatomies, genome expression, and genome replication and evolution. With some small changes, the order of chapters remains unchanged.
Content of Genomes 4th Edition
CHAPTER 1 GENOMES, TRANSCRIPTOMES, AND PROTEOMES 1
CHAPTER 2 STUDYING DNA 27
CHAPTER 3 MAPPING GENOMES 55
CHAPTER 4 SEQUENCING GENOMES 87
CHAPTER 5 GENOME ANNOTATION 119
CHAPTER 6 IDENTIFYING GENE FUNCTIONS 135
CHAPTER 7 EUKARYOTIC NUCLEAR GENOMES 155
CHAPTER 8 GENOMES OF PROKARYOTES AND EUKARYOTIC ORGANELLES 181
CHAPTER 9 MOBILE GENETIC ELEMENTS AND VIRAL GENOMES 203
CHAPTER 10 ACCESSING THE GENOME 219
CHAPTER 11 DNA BINDING PROTEINS IN GENOME EXPRESSION 241
CHAPTER 12 TRANSCRIPTOMES 257
CHAPTER 13 PROTEOMES 293
CHAPTER 14 GENOME EXPRESSION IN THE CONTEXT OF CELL AND ORGANISM 329
CHAPTER 15 GENOME REPLICATION 357
CHAPTER 16 MUTATIONS AND DNA REPAIR 389
CHAPTER 17 RECOMBINATION AND TRANSPOSITION 411
CHAPTER 18 HOW GENOMES EVOLVE 429
GLOSSARY 463
INDEX 491
CHAPTER 2 STUDYING DNA 27
CHAPTER 3 MAPPING GENOMES 55
CHAPTER 4 SEQUENCING GENOMES 87
CHAPTER 5 GENOME ANNOTATION 119
CHAPTER 6 IDENTIFYING GENE FUNCTIONS 135
CHAPTER 7 EUKARYOTIC NUCLEAR GENOMES 155
CHAPTER 8 GENOMES OF PROKARYOTES AND EUKARYOTIC ORGANELLES 181
CHAPTER 9 MOBILE GENETIC ELEMENTS AND VIRAL GENOMES 203
CHAPTER 10 ACCESSING THE GENOME 219
CHAPTER 11 DNA BINDING PROTEINS IN GENOME EXPRESSION 241
CHAPTER 12 TRANSCRIPTOMES 257
CHAPTER 13 PROTEOMES 293
CHAPTER 14 GENOME EXPRESSION IN THE CONTEXT OF CELL AND ORGANISM 329
CHAPTER 15 GENOME REPLICATION 357
CHAPTER 16 MUTATIONS AND DNA REPAIR 389
CHAPTER 17 RECOMBINATION AND TRANSPOSITION 411
CHAPTER 18 HOW GENOMES EVOLVE 429
GLOSSARY 463
INDEX 491
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