Genomes 4 by T.A. Brown (PDF) Download

Genomes
 
Author:
T.A. Brown
Publisher: Garland Science
ISBN No: 978-0815-3-4508-4
Release at: 2018
Pages: 539
Edition:
4th Edition
File Size: 78 MB
File Type: pdf
Language: English



Description of Genomes 4th Edition


Genomes 4th edition written by T.A. Brown is a great book for Genetics related studies available in ebook (PDF) to get a printable download. There have been remarkable advances in our knowledge of genomes since the previous edition of this book was published ten years ago. Back in 2007, next-generation sequencing was in its infancy and high-throughput meth-ods for transcriptomics and proteomics were only beginning to be exploited. The application of these methods over the last ten years has resulted in an exponential increase in the number of species for which genome sequences and annotations are now available and single species to be examined by multiple versions of the genome. 

The profusion of new sequences has had a particularly dramatic impact on bacterial genomics, with the introduction of the pan-genome concept and the discovery of extensive lateral transfer of genes between species. Our knowledge of eukaryotic genomes has an under-gone equally dramatic change, with the discovery of new types of noncoding RNA, including the vast numbers of long RNAs that are transcribed from the supposedly intergenic regions of many genomes

Genomes 4th edition retains the overall structure of the previous editions, with the book divided into four parts, on genome sequencing and annotation, genome anatomies, genome expression, and genome replication and evolution. With some small changes, the order of chapters remains unchanged.

Content of Genomes 4th Edition



CHAPTER 1 GENOMES, TRANSCRIPTOMES, AND PROTEOMES 1

CHAPTER 2 STUDYING DNA 27 

CHAPTER 3 MAPPING GENOMES 55 

CHAPTER 4 SEQUENCING GENOMES 87 

CHAPTER 5 GENOME ANNOTATION 119 

CHAPTER 6 IDENTIFYING GENE FUNCTIONS 135 

CHAPTER 7 EUKARYOTIC NUCLEAR GENOMES 155 

CHAPTER 8 GENOMES OF PROKARYOTES AND EUKARYOTIC ORGANELLES 181 

CHAPTER 9 MOBILE GENETIC ELEMENTS AND VIRAL GENOMES 203 

CHAPTER 10 ACCESSING THE GENOME 219 

CHAPTER 11 DNA BINDING PROTEINS IN GENOME EXPRESSION 241 

CHAPTER 12 TRANSCRIPTOMES 257 

CHAPTER 13 PROTEOMES 293 

CHAPTER 14 GENOME EXPRESSION IN THE CONTEXT OF CELL AND ORGANISM 329 

CHAPTER 15 GENOME REPLICATION 357 

CHAPTER 16 MUTATIONS AND DNA REPAIR 389 

CHAPTER 17 RECOMBINATION AND TRANSPOSITION 411 

CHAPTER 18 HOW GENOMES EVOLVE 429 

GLOSSARY 463 

INDEX 491 

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