Molecular Biology of the Gene 7th Edition (PDF)

Molecular Biology of the Gene 7th Edition (PDF)
Author: James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann,
Michael Levine, Richard Losick
Release at: 2013
Pages: 911
Edition: 7th Edition
File Size: 65 MB
File Type: PDF
Language: English



Description of Veterinary Molecular Biology of the Gene 7th Edition (PDF)

Molecular Biology of the Gene 7th Edition by James. D. Watson, Tania. A. Baker and Et al. is a great book, available in PDF download. This Molecular Biology of the Gene 7th Edition Book appears in this, it is 7th edition, on the 60th anniversary of the discovery of the structure of DNA in 1953, an occasion celebrated by our cover design. The double-helical structure of DNA, held together by specific pairing between the bases on the two strands, has become one of the iconic images of science. After the end of the century, that image had in turn given way to the double helix. The field of molecular biology as we understand it today was born out of the discovery of the DNA structure and the agenda for research that structure immediately provided. The paper by Crick-Watson proposing the famous double helix sentence: “It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.

The structure suggested how DNA could replicate, opening the way to investigate, in molecular terms, how genes are passed down through generations. It was also immediately apparent that the order of bases along a DNA molecule could represent a “genetic code,” and so an attack on that second great mystery of genetics—how genes encode characteristics—could also be launched. By the time the first edition of Molecular Biology of the Gene was published, just 12 years later in 1965, it had been confirmed that DNA replicated in the manner suggested by the model, the genetic code had all but been cracked, and the mechanism by which genes are expressed, and how that expression is regulated, had been established at least in outline. The field of molecular biology was ripe for its first textbook, defining for the first time the curriculum for undergraduate courses in this topic.

Our understanding of the mechanisms underlying these processes has hugely increased over the last 48 years since that first edition, often driven by technological advances, including DNA sequencing (another anniversary this year is the 10th anniversary of completion of the human genome project). The current edition of Molecular Biology of the Gene celebrates both the central intellectual framework of the field put in place in that first edition and the extraordinary mechanistic, biological, and evolutionary understanding that has since been achieved.




Content of Molecular Biology of the Gene 7th Edition (PDF)


PART I: HISTORY

Chapter 1: The Mendelian View of the World

Chapter 2: Nucleic Acids Convey Genetic Information

PART II: STRUCTURE AND STUDY OF MACRO-MOLECULES

Chapter 3: The Importance of Weak and Strong Chemical Bonds

Chapter 4: The Structure of DNA

Chapter 5: The Structure and Versatility of RNA

Chapter 6: The Structure of Proteins

Chapter 7: Techniques of Molecular Biology

PART II: MAINTENANCE OF THE GENOME

Chapter 8: Genome Structure, Chromatin, and the Nucleosome

Chapter 9: The Replication of DNA

Chapter 10: The Mutability and Repair of DNA

Chapter 11: Homologous Recombination at the Molecular Level

Chapter 12: Site-Specific Recombination and Transposition of DNA

PART IV: EXPRESSION OF THE GENOME

Chapter 13: Mechanisms of Transcription

Chapter 14: RNA Splicing

Chapter 15: Translation

Chapter 16: The Genetic Code

Chapter 17: The Origin and Early Evolution of Life

PART V: REGULATION

Chapter 18: Transcriptional Regulation in Prokaryotes

Chapter 19: Transcriptional Regulation in Eukaryotes

Chapter 20: Regulatory RNAs

Chapter 21: Gene Regulation in Development and Evolution

Chapter 22: Systems Biology

PART VI: APPENDICES

Apendix 1: Model Organisms

Apendix 2: Answers

INDEX

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