The Clinical Practice of Stem-Cell Transplantation (PDF)

The Clinical Practice of Stem-Cell  Transplantation

Author: John Barrett & Jennifer G.Treleaven
Release at: 1998
Pages: 658
Edition: 1st Edition
File Size: 6 MB
File Type: PDF
Language: English



Description of The Clinical Practice of Stem-Cell Transplantation (PDF)

The Clinical Practice of Stem-Cell Transplantation written by J Barrett & JG.Treleaven is a great Clinical Practice book for medical students available in (PDF) download. A prerequisite for successful stem-cell transplantation is a coordinated team approach. Procedures are complex, and require haematological, general medical, surgical, psychological, nursing and laboratory input. Management is very interventive, both in terms of diagnosis and treatment, and requires a high degree of understanding between care team and patient.

In recent years, there has been a rapid expansion in the use of stem-cell transplantation worldwide, with new transplant teams coming into being each year. New specialists and new teams need practical information about the application of stem-cell transplantation in clinical practice, and the procedures involved. It is not always easy to obtain such information quickly and concisely. The indications for stem-cell transplantation have expanded considerably, and its place in treatment programmes is now much better defined. As these refinements have occurred and the procedure has become safer, more disease categories have become amenable to stem cell transplantation as a treatment approach, for example, chronic lymphocytic leukaemia, breast cancer, and autoimmune diseases. Also, patients are now better informed about treatment options. Treatment decisions have to be made very rapidly, and there are still many areas of controversy. Protocol books can help, but by their nature they rarely contain reference to the reasons behind the practice laid down. It is also difficult to keep protocol books either up-to-date, complete, or easy to locate on the unit.

With these considerations in mind, we have compiled this book which represents current transplantation practice across the entire discipline. It covers autologous and allogeneic transplantation using marrow, peripheral blood stem cells and cord blood, for the treatment of malignant and non-malignant conditions. There are four main sections: the first covers the place of stem cell transplantation in the treatment of the various malignant and non-malignant conditions. The second deals with the practical aspects of transplantation of relevance prior to the transplant, and the third section deals with practical issues occurring after the transplant. Finally, the fourth section is concerned with more general issues such as out-patient management and setting up transplant units. All of the contributors have had first-hand experience in clinical BMT, in the USA, Europe and Great Britain. We hope that with our broad choice of experts, we have succeeded in avoiding bias relating to a particular unit and that, as far as possible, the views presented reflect those generally accepted.




Content of The Clinical Practice of Stem-Cell Transplantation (PDF)


Part 1 THE PLACE OF STEM-CELL TRANSPLANTATION IN THE TREATMENT OF MALIGNANT AND NON-MALIGNANT DISORDERS

Chapter 1: Introduction

Chapter 2: Theoretical aspects of dose intensity and dose scheduling

Chapter 3: myeloid leukaemia

Chapter 4: Chronic myeloid leukaemia

Chapter 5: Adult acute lymphoblastic leukaemia

Chapter 6: Paediatric leukaemias

Chapter 7: The myelodysplastic syndromes and acute myeloid leukaemia following myelodysplastic syndrome

Chapter 8: Multiple myeloma

Chapter 9: Hodgkin’s disease

Chapter 10: Non-Hodgkin’s lymphoma

Chapter 11: Solid tumours in children

Chapter 12: Breast cancer Pablo

Chapter 13: Solid tumours in adults (excluding breast and germ cell)

Chapter 14: Germ-cell tumours

Chapter 15: Immunodeficiency diseases

Chapter 16: Aplastic anaemia

Chapter 17: Fanconi anaemia Eliane

Chapter 18: Thalassaemia

Chapter 19: Sickle cell anaemia Christiane

Chapter 20: Lysosomal storage diseases

Chapter 21: Chronic lymphocytic leukaemia

Chapter 22: Autoimmune disorders

Part 2 PRACTICAL ASPECTS OF STEM-CELL TRANSPLANTATION

Chapter 23: Pre-transplant evaluation of the patient and donor

Chapter 24: HLA matching and compatibility testing

Chapter 25: Searching the Registry for an unrelated donor Susan Cleaver

Chapter 26: Unrelated donor bone-marrow transplantation Jacqueline

Chapter 27: Allogeneic related partially mismatched transplantation P.Jean

Chapter 28: Venous access

Chapter 29: Marrow collection and processing

Chapter 30: Use of cord blood

Chapter 31: Peripheral blood stem cells for autologous and allogeneic transplantation

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